Evidence-based health, wellness, and the science of living well.

Tiny plastic particles in drinking water may be doing more than contaminating the environment. New research suggests nanoplastics can actually help harmful bacteria survive by strengthening the slimy biofilms they form inside water systems. These tougher biofilms become more resi

A drug originally developed for spinal cord injury may offer a fresh approach to treating Alzheimer’s disease. In mouse studies, KCL-286 repaired dangerous DNA damage, reduced inflammation, and targeted multiple disease-related pathways instead of focusing on just amyloid or tau.

An unusual leopard gecko that naturally develops aggressive tumors may become an important new model for cancer research. Scientists found its tumors share key genetic changes with human cancers, offering a rare opportunity to study the disease as it develops naturally.

Where you live could shape your dementia risk, massive study finds and more — today's prescription signal.

Researchers found that semaglutide, the active ingredient in Ozempic and Wegovy, slowed biological aging markers in adults with HIV, marking the first clinical evidence that the drug may influence human aging. Although the findings are encouraging, scientists say larger studies a

Where you live could shape your dementia risk, massive study finds and more — today's prescription signal.

Researchers analyzing data from more than 214,000 people found that dementia risk factors differ widely across countries, challenging the idea of a one-size-fits-all prevention strategy. At the same time, they uncovered surprisingly consistent patterns that could help shape smart

Yale scientists discovered two neuron surface proteins that appear to help spread the toxic protein linked to Parkinson’s disease. Blocking these proteins in mice dramatically reduced disease progression, offering a potential new target for future therapies.

A new study found that dietary fiber can determine whether beneficial intestinal worms help reduce inflammation or become essentially inactive. With plenty of fiber, the worms remained healthy and supported an anti-inflammatory response, while a low-fiber diet pushed them into a

A new study debunks the long-standing claim that baby rattlesnakes are more dangerous than adults. Researchers found that young rattlesnakes can control their venom just like adults, while adult snakes usually inject much more venom and cause more serious bites. The team also unc

Tiny silica nanoparticles engineered to seek out prostate cancer caused tumor cells to self-destruct and supercharged the immune system in preclinical mouse studies. Combined with immunotherapy, the treatment produced complete remissions in multiple mice, raising hopes for a powe

Almost half of the takeaway meals tested contained more salt than advertised, with some dishes delivering nearly twice the recommended daily limit in a single serving. Surprisingly, classic fish and chips ranked among the lowest-salt options, while pasta, pizza, and curries were

The mysterious sound known as The Hum has been reported worldwide for decades, yet its source often remains impossible to find. Researchers tested whether people who hear it have exceptional low-frequency hearing or measurable sounds produced inside their ears, but neither explan

Scientists may have uncovered one reason coffee is repeatedly associated with healthier aging and lower disease risk. Compounds in coffee appear to activate NR4A1, a receptor that helps protect cells from stress, inflammation, and damage. These protective effects disappeared when

A low-cost antidepressant may offer new hope for people struggling with long COVID fatigue. In a randomized clinical trial involving 399 adults, fluvoxamine significantly reduced fatigue and improved quality of life compared with a placebo, making it one of the first medications

Several popular sugar substitutes may not be as harmless as they seem. Adults who consumed the most artificial sweeteners showed substantially faster declines in memory and thinking, especially if they were under 60 or had diabetes. The highest intake was linked to cognitive agin

A 12-week intermittent fasting program produced weight-loss benefits that were still visible a year later. Participants who ate within an eight-hour window maintained more weight loss than those who followed their usual longer eating schedule. Both early and late eating windows w

The Mediterranean diet may influence aging through tiny proteins produced inside the cell’s mitochondria. Older adults who followed the diet most closely had higher levels of humanin and SHMOOSE, which have been linked to heart and brain protection. Olive oil, fish, legumes, and

Tiny plastic particles in drinking water may be doing more than contaminating the environment. New research suggests nanoplastics can actually help harmful bacteria survive by strengthening the slimy biofilms they form inside water systems. These tougher biofilms become more resi

A large laboratory study found that many commonly used sweeteners can directly change the growth of gut bacteria. Researchers identified more than 100 cases in which sweeteners behaved differently when combined with medications, caffeine, or flavorings. The combination of isostev

A drug originally developed for spinal cord injury may offer a fresh approach to treating Alzheimer’s disease. In mouse studies, KCL-286 repaired dangerous DNA damage, reduced inflammation, and targeted multiple disease-related pathways instead of focusing on just amyloid or tau.

A new experimental treatment may have found a way to outsmart glioblastoma’s toughest defense: the blood-brain barrier. Researchers used sugar-coated nanoparticles to ferry genetic instructions that restore a key tumor-suppressing protein directly into brain cancer cells. In mous

An international study found that finerenone slows kidney function decline and reduces the risk of serious kidney and cardiovascular complications in people with chronic kidney disease who do not have diabetes. The results could open the door to a much-needed new treatment option

Researchers solved a long-standing mystery behind how a bacterial toxin associated with colorectal cancer damages the colon. The toxin first binds to a receptor called claudin-4, giving it access to attack the cells' protective barrier. After identifying this weak point, the team